Modulates Cytokines and Chemokines

　Thymosin beta-4 upregulates anti-oxidative enzymes and protects human cornea epithelial cells against oxidative damage.

Ho JH et. al.
Br J Ophthalmol. 2008 Jul;92(7):992-7. doi: 10.1136/bjo.2007.136747. Epub 2008 May 14.

　Protection of thymosin beta-4 on corneal endothelial cells from UVB-induced apoptosis.

Ho JH et. al.
Chin J Physiol. 2010 Jun 30;53(3):190-5.

　Thymosin beta4 is an essential paracrine factor of embryonic endothelial progenitor cell-mediated cardioprotection.

Hinkel R et. al.
Circulation. 2008 Apr 29;117(17):2232-40. doi: 10.1161/CIRCULATIONAHA.107.758904. Epub 2008 Apr 21.

　Embryonic endothelial progenitor cell-mediated cardioprotection requires Thymosin beta4.

Kupatt C et. al.
Trends Cardiovasc Med. 2008 Aug;18(6):205-10. doi: 10.1016/j.tcm.2008.10.002.